Fast UK dispatch · Third-party tested · Lot-matched certificates
Mitochondrial
MOTS-c peptide pen
- Type:
- Mitochondrial-derived 16mer peptide.
- Form:
- Ready-to-use liquid solution in a 20mg research cartridge.
- Application:
- AMPK pathway activation
MOTS-c
20MG
20mg · Ready to use
£8.95 per mg · 20mg total
£179.00
Choose your pack
Lot-matched 3rd party CoA with every batch
Qty
Certificate of analysis
Independent test results for this batch, tested by Janoshik Analytical.
Batch MRL-26Q3-A06
MS
Mass-spec confirmed identity
LAL
Endotoxin tested to established limits
UK
Synthesised and tested in Britain
What's in the cartridge
Supplied as a liquid peptide solution in a 3ml research cartridge. Contains MOTS-c (20mg). A 16-amino-acid peptide encoded within the mitochondrial 12S rRNA, activating AMPK signalling and studied in metabolic and exercise-physiology research.
Specifications
Format
Liquid peptide solution, 20mg
Molecular formula
C₁₀₁H₁₅₂N₂₈O₂₂S₂
Molecular weight
2174.64 g/mol
Abbreviation
MOTSC
Vials vs Pens
11 Steps. Or one.
A vial arrives as powder that has to be prepared, measured and transferred by hand. The Mercia Pen arrives pre-filled.
Traditional Vial
Mercia Pen
11 steps
prepare, measure, transfer
1 step
load the cartridge
~12 minutes
plus a 5 minute wait mid-way
12 seconds
ready when you are
Hand-measured
read from graduated markings
Fixed mechanism
consistent every time
Opened repeatedly
repeated access to the contents
Factory-sealed
never opened, never mixed
Extra consumables
diluent and accessories
Nothing else
everything is in the pen
Handling and storage
Store
Store immediately at 2–8°C upon delivery. Do not freeze.
Shipping
Shipped in validated temperature-controlled packaging to maintain product stability during transit.
Avoid Freezing
Do not freeze, as freezing may compromise product quality.
Temperature Tolerance
Stabilised below 25°C for delivery. Should not be exposed to higher temperatures.
3rd Party Tested
Independently tested for heavy metals, residual solvents and endotoxins to established limits.
Full Traceability
Batch-level traceability from production to delivery.
Certificate of Analysis
Lot-matched 3rd party CoA with every batch. Available on our website.
Shelf Life
12 months from manufacture when stored at 2–8°C.
What customers say
Research overview
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c), also written MOTSC or MOTS C, is a 16-amino-acid peptide encoded within the mitochondrial genome — specifically within the 12S ribosomal RNA gene. UK researchers looking to buy MOTS-c will find it supplied here as a UK-manufactured liquid peptide solution in a 3ml research cartridge. Its discovery represented a significant advance in understanding mitochondrial-derived signalling peptides.
AMPK Pathway Activation
The most studied mechanism of MOTS-c involves AMPK (AMP-activated protein kinase) activation. Research has examined its role in cellular energy sensing and AMPK phosphorylation, downstream effects on glucose uptake and fatty acid oxidation, and the relationship between mitochondrial peptide signalling and whole-cell metabolic adaptation.
Mitochondrial Bioenergetics
As a mitochondrially-encoded peptide, MOTS-c has been studied in the context of mitochondrial function itself. Research has investigated its effects on mitochondrial membrane potential and respiration, interactions with the electron transport chain, and its role in mitochondrial stress responses.
Metabolic and Insulin Sensitivity Research
MOTS-c has attracted significant interest in metabolic research. Studies have examined its effects on insulin sensitivity in skeletal muscle models, glucose transporter expression and translocation, and interactions with obesity-related metabolic dysregulation in preclinical models.
Exercise Physiology Research
MOTS-c levels have been observed to change in response to exercise in animal models, making it a subject of interest in exercise physiology research, including studies of skeletal muscle adaptation, endurance capacity, and the mitochondrial response to physical stress.
For laboratory research use only. Not intended for human or animal consumption.
Frequently asked questions
Is a Certificate of Analysis included?+
Yes. Every order ships with a third-party CoA matched to the lot number printed on your cartridge. A sample CoA is available on the site.
How is purity verified?+
Each batch is HPLC-tested for purity and mass-spec confirmed for identity, then tested for heavy metals, residual solvents and endotoxins.
Does the solution need reconstituting?+
No. The cartridge is supplied as a ready-to-use liquid solution in 3ml bacteriostatic water.
How is it shipped and stored?+
Validated temperature-controlled packaging, UK next-day dispatch. Store at 2–8°C on arrival, do not freeze, 12-month shelf life.
Who is this supplied to?+
Qualified personnel for in vitro laboratory research and analytical work only. Not for human or animal consumption.
