NAD+ 500mg
Nicotinamide adenine dinucleotide.
A central cellular cofactor for redox reactions and sirtuin/PARP activity. Researched in cellular bioenergetics, sirtuin signalling, and longevity models.
£149.00
Cartridge
500mg
Lot-matched 3rd party CoA with every batch
Qty
Research applications
Molecular Formula
C₂₁H₂₇N₇O₁₄P₂
Molecular weight
663.43 g/mol
Purity
99.61%
Abbreviation
NAD
Liquid Peptide Solution
The cartridge contains a liquid peptide formulation of 3ml BAC Water and the stated peptide milligram content. The solution is prepared under controlled conditions and verified for concentration and purity before dispatch.
Product Information
Store
Store immediately at 2–8°C upon delivery. Do not freeze.
Shipping
Shipped in validated temperature-controlled packaging to maintain product stability during transit.
Avoid Freezing
Do not freeze, as freezing may compromise product quality.
Temperature Tolerance
Stabilised below 25°C for delivery. Should not be exposed to higher temperatures.
3rd Party Tested
Independently tested for heavy metals, residual solvents and endotoxins to established limits.
Full Traceability
Batch-level traceability from production to delivery.
Certificate of Analysis
Lot-matched 3rd party CoA with every batch. Available on our website.
Shelf Life
12 months from manufacture when stored at 2–8°C.
Research Overview
NAD+ (Nicotinamide Adenine Dinucleotide), also written NAD or NAD Plus, is a central coenzyme found in all living cells. Supplied here as a UK-manufactured liquid peptide solution for researchers looking to buy NAD+ in the UK, it plays a fundamental role in cellular energy metabolism and serves as a substrate for several classes of regulatory enzymes. Its decline with age has made it a major focus of longevity and metabolic research.
Sirtuin Pathway Research
NAD+ is an obligatory substrate for the sirtuin family of NAD+-dependent deacylases (SIRT1–7). Research has examined NAD+'s role in regulating sirtuin enzymatic activity, sirtuin-mediated histone deacetylation and gene expression changes, and the relationship between cellular NAD+ levels and sirtuin-dependent metabolic regulation.
PARP Activity and DNA Repair
Poly(ADP-ribose) polymerases (PARPs) consume NAD+ during DNA damage repair. Research has investigated the competition between PARP activity and sirtuin function for cellular NAD+ pools, NAD+ depletion as a consequence of DNA damage-induced PARP hyperactivation, and strategies to maintain NAD+ availability in models of genotoxic stress.
Mitochondrial Electron Transport
NAD+ and its reduced form NADH are central to mitochondrial oxidative phosphorylation. Research has examined NAD+/NADH ratio dynamics in mitochondrial function, the role of complex I in NADH oxidation and ATP generation, and mitochondrial NAD+ pools as distinct from cytosolic pools in cellular energy models.
Longevity and Cellular Bioenergetics
The decline of cellular NAD+ with age has positioned it as a key subject in longevity research, including studies of NAD+ precursor supplementation effects, the relationship between NAD+ levels and age-related metabolic dysfunction, and interactions with other longevity-associated pathways including AMPK and mTOR.
For laboratory research use only. Not intended for human or animal consumption.
Certificate of Analysis
Every batch ships with a lot-matched, third-party Certificate of Analysis.
Referenced by
Really impressed with the service. Ordered in the afternoon and everything arrived the next day. The temperature controlled packaging was a nice touch and the CoA with matching batch number gave me confidence in the quality.
James Walker
Excellent experience from start to finish. Fast 24-hour delivery, securely packaged and everything arrived cold. Batch numbers matched the documentation and the certificate of analysis was included.
Sarah Mitchell
Very professional service. Communication was great, delivery was incredibly quick and the insulated packaging kept everything in perfect condition. Nice to see full CoA documentation included.
Daniel Harris
First order and definitely won't be my last. Arrived within 24 hours, well protected and temperature controlled.
Emily Carter
Couldn't fault the experience. Easy ordering process, next-day delivery and excellent packaging.
Michael Turner
Really impressed with the service. Ordered in the afternoon and everything arrived the next day. The temperature controlled packaging was a nice touch and the CoA with matching batch number gave me confidence in the quality.
James Walker
Excellent experience from start to finish. Fast 24-hour delivery, securely packaged and everything arrived cold. Batch numbers matched the documentation and the certificate of analysis was included.
Sarah Mitchell
Very professional service. Communication was great, delivery was incredibly quick and the insulated packaging kept everything in perfect condition. Nice to see full CoA documentation included.
Daniel Harris
First order and definitely won't be my last. Arrived within 24 hours, well protected and temperature controlled.
Emily Carter
Couldn't fault the experience. Easy ordering process, next-day delivery and excellent packaging.
Michael Turner
