Lot 24-6012
Selank · 20mg
Research applications
- GABAergic anxiolytic models
- BDNF/serotonergic research
- Immune-modulation pathways
Sequence
Thr-Lys-Pro-Arg-Pro-Gly-Pro
Molecular weight
751.88 g/mol
Purity
≥98.8%
Abbreviation
SEL
Storage
Lyophilized: −20 °C. Reconstituted: 2–8 °C, 30 days.
Reconstitution
Add 2 mL BAC water to a 5 mg vial → 2.5 mg/mL.
Selank
Synthetic heptapeptide tuftsin analogue.
A Russian-developed heptapeptide analogue of the immunomodulator tuftsin. Studied in anxiolytic and nootropic rodent models.
Configure
£125.00
Vial size
Lot 24-6012 · lot-matched COA included · cold-chain shipping
Qty
Research Overview
Selank is a synthetic heptapeptide analogue of the endogenous immunomodulatory tetrapeptide tuftsin (Thr-Lys-Pro-Arg). Developed at the Institute of Molecular Genetics of the Russian Academy of Sciences, it has been studied in a range of neurological and immunological research contexts.
GABAergic Anxiolytic Research
Selank has been investigated as a potential modulator of GABAergic neurotransmission. Research has examined its interactions with GABA-A receptor complexes and benzodiazepine binding sites, its effects on anxiety-related behaviour in rodent models such as elevated plus maze and open field tests, and comparisons with classical benzodiazepine pharmacology in preclinical settings.
BDNF and Serotonergic Pathways
Beyond GABAergic mechanisms, Selank research has explored neurotrophic and monoaminergic interactions. Studies have investigated its effects on brain-derived neurotrophic factor (BDNF) expression, serotonin metabolism and turnover in rodent brain tissue, and dopaminergic pathway interactions in cognitive performance models.
Immune Modulation Research
As a tuftsin analogue, Selank retains interactions with immunological pathways. Research has examined its effects on interleukin expression profiles, T-lymphocyte activity modulation, and the relationship between immune function and anxiety-related behaviour.
Cognitive Performance Models
Selank has also been studied in memory and learning models, including spatial navigation tasks, attention and working memory paradigms, and stress-induced cognitive impairment models.
For laboratory research use only. Not intended for human or animal consumption.