Lot 24-6211
Semax · 20mg
Research applications
- BDNF / NGF expression
- Ischemic recovery models
- Cognitive performance research
Sequence
Met-Glu-His-Phe-Pro-Gly-Pro
Molecular weight
878.99 g/mol
Purity
≥98.9%
Abbreviation
SMX
Storage
Lyophilized: −20 °C. Reconstituted: 2–8 °C, 30 days.
Reconstitution
Add 2 mL BAC water to a 5 mg vial → 2.5 mg/mL.
Semax
ACTH(4-10) analogue.
A synthetic ACTH(4-10) analogue developed in Russia. Studied in BDNF/NGF expression, neuroprotection, and ischemic recovery models.
Configure
£120.00
Vial size
Lot 24-6211 · lot-matched COA included · cold-chain shipping
Qty
Research Overview
Semax is a synthetic heptapeptide analogue of the ACTH(4-10) fragment of adrenocorticotropic hormone. Developed at the Institute of Molecular Genetics in Moscow, it has been the subject of extensive neurological research, particularly in the areas of neuroprotection and cognitive function.
BDNF and NGF Expression
One of the most studied aspects of Semax is its influence on neurotrophic factor expression. Research has examined its effects on brain-derived neurotrophic factor (BDNF) upregulation in hippocampal and cortical tissue, nerve growth factor (NGF) expression in preclinical models, and the downstream effects of neurotrophic signalling on neuronal survival and plasticity.
Neuroprotection Research
Semax has attracted interest in neuroprotective research contexts. Studies have investigated its protective effects in models of oxidative stress-induced neural damage, interactions with anti-apoptotic signalling cascades in neural tissue, and its effects on microglial activation and neuroinflammatory mediators.
Ischaemic Recovery Models
A significant body of preclinical research has examined Semax in cerebral ischaemia models. Research has explored its effects on infarct volume following experimental ischaemic events, neurovascular unit preservation in stroke models, and recovery of neurological function in preclinical settings.
Dopaminergic and Serotonergic Research
Semax has also been studied in relation to monoamine neurotransmitter systems, including dopamine receptor sensitivity modulation and serotonin turnover in brain regions associated with mood and cognition.
For laboratory research use only. Not intended for human or animal consumption.